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Kidney disease in patients with lupus who are treated with potent drugs that suppress the imune system

Article Abstract:

Cyclophosphamide alone or in combination with methylprednisolone appears to be more effective than methylprednisolone for treating lupus nephritis. Lupus nephritis is a kidney disease caused by lupus, an immunological disease.

Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 2001

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The treatment of lupus nephritis: revisiting Galen

Article Abstract:

Not all patients with lupus nephritis will be cured by cyclophosphamide given either alone or combined with methylprednisolone. Lupus nephritis is a kidney disease caused by lupus, and immunological disorder.

Author: Lewis, Edmund J.
Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 2001
Editorial

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Methylprednisolone and cyclophosphamide, alone or in combination, in patients with lupus nephritis: a randomized, controlled trial

Article Abstract:

Cyclophosphamide or cyclophosphamide in combination with methylprednisolone appears to be a better treatment for lupus patients with kidney inflammation compared with methylprednisolone alone. Researchers assigned 82 lupus patients with kidney inflammation to monthly intravenous treatment with either methylprednisolone, cyclophosphamide, or a combination of both. Eighty-five percent of the combination therapy group and 62% of the cyclophosphamide group returned permanently to normal kidney function versus 29% of the methylprednisolone group.

Author: Klippel, John H., Balow, James E., Boumpas, Dimitrios T., Steinberg, Alfred D., Gourley, Mark F., Muir, Joanne, Scott, Dorothy, Austin, Howard A., III, Yarboro, Cheryl H., Vaughan, Ellen M.
Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1996
Complications and side effects

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Subjects list: Evaluation, Drug therapy, Systemic lupus erythematosus, Kidney diseases, Methylprednisolone, Complications, Cyclophosphamide
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