Fifty years of dental, oral and craniofacial research: the National Institute of Dental Research's Division of Intramural Research

Article Abstract:

The Division of Intramural Research (DIR) of the National Institute of Dental Research (NIDR) has played an important role in dental research. Although the division was created in 1996, intramural research has been the focus of NIDR since its inception in 1948. About 350 staff members work in the DIR and include scientists, students and support staff. The intramural program first recognized that bacteria are responsible for dental cavities and scientists working at the institute's Bethesda, MD, campus have made many other significant contributions to dentistry.

Research, History, Tooth diseases, Dental research, United States. National Institute of Dental Research

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The role of the oral environment in HIV-1 transmission

Article Abstract:

Several proteins produced by saliva appear to account partly for the lowered risk of transmitting HIV via saliva. Although mucosal transmission via the anus and vagina account for many cases, this is not true of the oral mucosa. Epidemiologic studies have consistently shown that the virus is not transmitted by kissing or sharing eating utensils. Studies have shown that the virus is found in saliva but saliva also has mucins as well as a protein called secretory leukocyte protease inhibitor, which appear to block infection of oral epithelial cells by HIV.

Physiological aspects, HIV infection, HIV infections, Disease transmission, Saliva, Mouth, Stomatognathic system

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