Effect of intravenous albumin on renal impairment and mortality in patients with cirrhosis and spontaneous bacterial peritonitis

Article Abstract:

Albumin appears to reduce the risk of kidney failure and death in patients with liver cirrhosis and spontaneous bacterial peritonitis. Albumin is a plasma protein used to expand the blood volume. Researchers compared 126 patients with the liver disease and the abdominal infection treated with antibiotics and albumin, or antibiotics alone. The infection resolved in almost every patient. Kidney failure developed in 10% of the patients who received albumin and 33% of the patients given only antibiotics. Death was nearly twice as common among patients given only antibiotics, compared to those given antibiotics and albumin.

Spain, Statistical Data Included, Evaluation, Prevention, Drug therapy, Peritonitis, Acute renal failure, Acute kidney failure, Albumin

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Current concepts: management of cirrhosis and ascites

Article Abstract:

Ascites is the most common complication of cirrhosis and is associated with a poor quality of life, increased risks of infections and renal failure. Cirrhosis, most frequently caused by hepatitis C or alcoholism, was the 12th leading cause of death in the United States in 2000, accounting for more than 25,000 deaths.

United States, Diagnosis, Complications and side effects, Risk factors, Ascites, Alcoholic liver diseases

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