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The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis

Article Abstract:

Parathyroid hormone and alendronate together are not more effective for treating osteoporosis than either one alone, according to a study of 238 postmenopausal women. Parathyroid hormone stimulates bone growth and alendronate prevents bone destruction. So researchers believed the two treatments would be better than either one alone. Further research will be necessary to determine whether this is true.

Author: Palermo, Lisa, Ensrud, Kristine E., Black, Dennis M., Rosen, Clifford J., Bilezikian, John P., Greenspan, Susan L., McGowan, Joan A., Lang, Thomas F., Garnero, Patrick, Bouxsein, Mary L.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2003
Evaluation

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One year of alendronate after one year of parathyroid hormone (1-84) for osteoporosis

Article Abstract:

An attempt is made to question whether antiresorptive therapy is required to maintain gains in bone mineral density after one year of therapy with parathyroid hormone. It is concluded that after one year of parathyroid hormone (1-84), densitometric gains appear to be maintained or increased with alendronate but lost if an antiresorptive agent does not follow parathyroid hormone.

Author: Palermo, Lisa, Ensrud, Kristine E., Black, Dennis M., Rosen, Clifford J., Bilezikian, John P., Greenspan, Susan L., McGowan, Joan A., Lang, Thomas F., Hue Trisha
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
Science & research, New England States, Health aspects, Research, Women, Hormone therapy, Women's health, New England

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Subjects list: Care and treatment, Parathyroid hormone, Parathyroid hormones, Osteoporosis, Alendronate
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