Pemetrexed (Alimta) for mesothelioma

Article Abstract:

Pemetrexed is an antimetabolite that inhibits several enzymes involved in folate metabolism, including dihydrofolate reductase, thymidylate synthase and glycinamide ribonucleotide formyltransferase. The most common adverse effect of pemetrexed is myleosupression rash, fatigue, mouth sores, nausea and diarrhea; the cost of one dose for an average size adult would be about $5000.

United States, Analysis, Risk factors, Folic acid, Ribonucleotides, Chemical properties

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Pleural effusion: from diagnostic thoracentesis to thoracoscopy

Article Abstract:

It is sometimes difficult to diagnose pleural effusion correctly. The physician may have to rely on a variety of tests and procedures if a simple chest examination fails to diagnose the effusion. Diagnostics include imaging studies, thoracentesis, closed-needle pleural biopsy, and thoracoscopy. The latter technique approaches a diagnostic accuracy of 95%.

Chest, Pleural effusions, Pleural effusion, Thoracentesis, Thoracoscopy

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Malignant pleural mesothelioma

Article Abstract:

Malignant pleural mesothelioma is a respiratory disease which is associated with people who have been exposed to asbestos and which is becoming more common. The symptoms of the disease and the care of patients are discussed.

Pleural diseases

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