Persistence of lamivudine-sensitive HIV-1 quasispecies in the presence of lamivudine in vitro and in vivo

Article Abstract:

The changes in viral populations in HIV-1-infected patients treated with zidovudine/lamivudine and subsequent failing therapy are analyzed. The analysis has shown that lamivudine-sensitive and lamivudine-resistant HIV-1 variants are able to persist despite highly unfavorable conditions in vivo and in vitro and that selective advantages of viral variants can change depending on the complexity of other simultaneously replicating viral variants.

United States, Science & research, Research, Observations, Polymerase chain reaction, Dosage and administration, Virus replication, Lamivudine

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Longitudinal anthropometric changes in HIV-infected and HIV-uninfected men

Article Abstract:

A study was conducted to compare longitudinal changes in anthropomorphic measurements among HIV-seronegative control subjects. It was found that mean waist and hip circumference increased considerably in all groups.

Analysis, Diagnosis, Body constitution

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