Pharmacologic treatment of acute traumatic brain injury

Article Abstract:

There are probably several reasons why clinical trials of drugs to treat brain injury have failed to show any benefit. Brain injury can be caused by many different conditions, not all of which will respond to one particular drug. Consequently, a subgroup of patients whose injury is caused by hemorrhage may respond to a drug that would not benefit patients whose injury is caused by nerve damage. In addition, many factors contribute to the injury and therefore a combination of drugs may be more beneficial. The timing and duration of drug administration is also critical.

Health aspects, Drug therapy, Free radical reactions

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Cognitive Rehabilitation for Traumatic Brain Injury: A Randomized Trial

Article Abstract:

An in-hospital rehabilitation program that focuses on intellectual function does not appear to be effective in the treatment of patients with traumatic brain injuries. This was the conclusion of a study in which 120 soldiers with a moderate to severe traumatic brain injury received this treatment or a less intensive program in their home. One year later, the percentage of soldiers who had returned to active duty or other employment was similar in both groups.

Prognosis, Soldiers, Rehabilitation

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Therapeutic hypothermia for severe traumatic brain injury

Article Abstract:

Lowering the body temperature of people with traumatic brain injury may improve their outcome, according to a study published in 2003. This study re-warmed the patients in 24 hours or less, which is quicker than many other studies. However, this can minimize the adverse effects of hypothermia. Other studies of hypothermia therapy for traumatic brain injury are underway, including one in children.

Care and treatment, Hypothermia, Induced, Induced hypothermia

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