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Predictive factors from cold knife conization for residual cervical intraepithelial neoplasia in subsequent hysterectomy

Article Abstract:

The presence or absence of abnormal cells in cervical tissue removed by cold knife conization may not predict whether such cells will be found in specimens obtained at subsequent hysterectomy. Of 1,272 women who had cold knife conization for cervical neoplasia, one-quarter had a hysterectomy within one year. Among 98% of patients with normal cells in the margins of the outer cervix, 33% had residual disease in the hysterectomy tissue sample whereas 40% of patients with abnormal cells in the outer cervical margin had residual disease. The same lack of correlation was found for dysplasia in the inner cervical margin or in the cervical glands. The only correlations with residual disease were the severity of the abnormality and the patient's age.

Author: Higgins, Robert V., Marroum, Marie-Claire, Moore, Barbara C., Laurent, Sherry L., Bellitt, Patricia
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1995
Surgery, Cervix uteri, Cervix uteri biopsy

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Management of low-grade squamous intraepithelial lesions during pregnancy

Article Abstract:

A procedure called a colposcopy does not seem to be necessary in pregnant women with mildly abnormal Pap smears. This procedure is used to examine the cervix and vagina in detail. Colposcopies were done on 253 pregnant women with smear results indicating low-grade squamous lesions, squamous atypia, or abnormal squamous cells. Nearly all of the women had either low-grade squamous lesions or were normal as determined by colposcopy. Most Pap smear results did not change after delivery. Four of 69 women biopsied after delivery were found to have high-grade squamous lesions. None had invasive cervical cancer.

Author: Higgins, Robert V., Jain, Astrid G., Boyle, Madeline J.
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1997
Medical examination, Pregnant women, Colposcopy

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Detection of Neisseria gonorrhoeae and Chlamydia trachomatis colonization of the gravid cervix

Article Abstract:

A Gram stain of cervical secretions can accurately detect most women who do not have gonorrhea or chlamydia. This technique is much cheaper than other assays such as enzyme immunoassay (ELISA), DNA probe hybridization and PCR. For this reason, it should be used as the initial test in population screening.

Author: Asbill, Kelly K., Higgins, Robert V., Bahrani-Mostafavi, Zarha, Vachris, Judy C., Kotrotsios, Steve H., Elliot, Mollie C., Price, Douglas K.
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2000
Evaluation, Stains and staining (Microscopy), Stains (Microscopy), Gonorrhea, Chlamydia infections

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Subjects list: Cervix dysplasia, Diagnosis
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