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Successful pregnancy in a neurologically impaired woman with Wilson's disease

Article Abstract:

Successful pregnancy in a patient with Wilson's disease may be possible with penicillamine therapy. Wilson's disease is a rare inherited disease involving liver excretion of copper and toxic buildup of copper in vital organs. A 30-year-old woman in the 11th week of her first pregnancy had been previously diagnosed with Wilson's disease. She experienced neurologic impairment from the disease. Oral penicillamine therapy was prescribed, and pyridoxine and diazepam were taken as needed. She was delivered of a healthy baby boy at 39 weeks of pregnancy. No copper deposits were observed in the placenta.

Author: Berghella, Vincenzo, Johnson, Anthony, Steele, Danae, Spector, Toba, Cambi, Franca
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1997
Health aspects, Diseases, Pregnant women, Wilson's disease, Penicillamine

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Targeted prenatal herpes simplex virus testing: Can we identify women at risk of transmission to the neonate?

Article Abstract:

The potential strategies to prevent neonatal herpes include herpes simplex virus (HSV) serologic testing and counseling of pregnant women and rapid HSV polymerase chain reaction testing of maternal genital secretions at delivery. The targeted testing of HSV would miss a substantial proportion of neonatal herpes.

Author: Wald, Anna, Gardella, Carolyn, Reed, Susan D., Mark, Karen E., Kim, H. Nina
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2006
Diagnosis, Prevention, Pregnancy, Complications of, Pregnancy complications, Herpes simplex

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