Effect of intravenous omeprazole on recurrent bleeding after endoscopic treatment of bleeding peptic ulcers

Article Abstract:

An intravenous infusion of the drug omeprazole may lower the risk of bleeding in patients treated surgically for a bleeding peptic ulcer. Omeprazole belongs to a group of drugs called proton pump inhibitors, which are often used to treat ulcers. Researchers randomly assigned 240 patients with a peptic ulcer to receive an intravenous infusion of omeprazole or a placebo for up to three days. All of the patients had been treated with endoscopic surgery, but studies have shown that bleeding can recur even after surgery. Bleeding recurred in 22% of the patients in the placebo group compared to 7% in the omeprazole group.

Evaluation, Peptic ulcer, Omeprazole

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Preventing recurrent upper gastrointestinal bleeding in patients with Helicobacter pylori infection who are taking low-dose aspirin or naproxen

Article Abstract:

Treatment to eradicate Helicobacter pylori infection of the stomach can reduce the risk of recurring gastrointestinal bleeding in patients who take aspirin. In patients who take other NSAIDs, the anti-ulcer drug omeprazole is more effective than Helicobacter pylori eradication in preventing recurring bleeding.

Complications and side effects, Helicobacter infections

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Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding

Article Abstract:

A comparison of clopidogrel is carried out with aspirin plus esomeprazole for the prevention of recurrent bleeding from ulcers in high-risk patients. Results reveal that among patients with a history of aspirin-induced ulcer bleeding whose ulcers had healed before they received the study treatment, aspirin plus esomeprazole was superior to clopidogrel in the prevention of recurrent ulcer bleeding.

United Kingdom, Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Aspirin, Aspirin Combinations, Ulcers, Dosage and administration

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