Prevention of early-onset invasive neonatal group B streptococcal disease in a private hospital setting: the superiority of culture-based protocols

Article Abstract:

Swabbing a pregnant woman's vagina and rectum and then culturing the fluid to see if it grows group B streptococci is an effective way to stop the transmission of the bacteria to the baby. Only women who test positive would be given antibiotics, and this completely prevented transmission in 9,304 deliveries.

Cultures (Biology)

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The effectiveness of risk-based intrapartum chemoprophylaxis for the prevention or early-onset neonatal group B streptococcal disease

Article Abstract:

Giving antibiotics to pregnant women who have risk factors for group B streptococcal infection can prevent the infection in over 80%, according to a study of 316 women. It is best to give the antibiotics at least two hours before delivery for greatest effectiveness.

Usage, Antibiotics

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Rapid intrapartum detection of group B streptococcal colonization with an enzyme immunoassay

Article Abstract:

Use of the ICON Strep B rapid immunoenzyme assay does not appear suitable for general screening of group B streptococcal infection. Severe group B streptococcal infections affect up to 15,000 newborn infants annually, most of which are acquired from the mother during delivery. The death rate from these infections is as high as 50% among premature infants. The new ICON Strep B immunoassay and the standard broth culture test were used to detect group B streptococcal colonization in vaginal samples taken from 424 pregnant women. Of 98 confirmed positive cultures, 90 showed light colonization. The Icon assay was positive in all eight women with heavy group B streptococcal colonization but was positive in only one of the 90 patients with light colonization. Of 79 of the infants born to women with light colonization, 19 were diagnosed with suspected streptococcal infection and three had severe infection.

Methods, Evaluation, Product/Service Evaluation, Diagnosis, Medical screening, Health screening, Enzyme-linked immunosorbent assay, ICON Strep B (Medical test kit)

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