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Prospects for an AIDS vaccine

Article Abstract:

Several theories of evidence indicate that development of an effective vaccine for HIV is going to be extremely difficult. A renewed, organized, focused effort is needed to overcome the inability to solve fundamental scientific questions, which is the root cause for why a successful vaccine is not currently within the grasp.

Author: Desrosiers, Ronald C.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2004
Prevention, AIDS (Disease)

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Reversion of CTL escape-variant immunodeficiency viruses in vivo

Article Abstract:

Engendering cytotoxic T-lymphocyte (CTL) responses is likely to be an important goal of HIV vaccines. Studies indicate that in absence of selective pressure upon transmission to new hosts, these original escape mutations can be lost, suggesting that some HIV CTL epitopes will be maintained in human populations.

Author: Friedrich, Thomas C, Dodds, Elizabeth J., Yant, Levi J., Vojnov, Lara, Rudersdorf, Richard
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2004
T cells, Antigenic determinants

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Subjects list: Research, United States, AIDS vaccines
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