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Public Health Implications of Antiretroviral Therapy and HIV Drug Resistance, Part 1

Article Abstract:

Development of drug-resistant HIV and poor patient compliance with antiviral drug therapy could compromise the effectiveness of antiretroviral treatment for HIV infection. The rapid rate of mutation in HIV can produce drug-resistant virus even after antiviral treatment has been initiated. Antiviral therapy reduces viral loads in blood and, possibly, in genital fluids, which can reduce the risk of HIV transmission. Poor compliance with treatment protocols increases the risk of developing drug-resistant infection, which has important public health implications.

Author: Friedland, Gerald, Wainberg, Mark A.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998

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Public Health Implications of Antiretroviral Therapy and HIV Drug Resistance, Part 2

Article Abstract:

Development of drug-resistant HIV and poor patient compliance with antiviral drug therapy could compromise the effectiveness of antiretroviral treatment for HIV infection. The rapid rate of mutation in HIV can produce drug-resistant virus even after antiviral treatment has been initiated. Antiviral therapy reduces viral loads in blood and, possibly, in genital fluids, which can reduce the risk of HIV transmission. Poor compliance with treatment protocols increases the risk of developing drug-resistant infection, which has important public health implications.

Author: Friedland, Gerald, Wainberg, Mark A
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998

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Public Health Implications of Antiretroviral Therapy and HIV Drug Resistance, Part 4

Article Abstract:

Development of drug-resistant HIV and poor patient compliance with antiviral drug therapy could compromise the effectiveness of antiretroviral treatment for HIV infection. The rapid rate of mutation in HIV can produce drug-resistant virus even after antiviral treatment has been initiated. Antiviral therapy reduces viral loads in blood and, possibly, in genital fluids, which can reduce the risk of HIV transmission. Poor compliance with treatment protocols increases the risk of developing drug-resistant infection, which has important public health implications.

Author: Friedland, Gerald, Wainberg, Mark A.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998

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Subjects list: Health aspects, Prevention, Physiological aspects, HIV infection, Drug therapy, HIV infections, Patient compliance, Drug resistance in microorganisms, Microbial drug resistance, Antiviral agents
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