Quinolone-resistant Neisseria gonorrhoeae in Hong Kong

Article Abstract:

The use of quinolone antibiotics to treat gonorrhea in Hong Kong may have led to the development of many strains of quinolone-resistant gonorrhea. Researchers in Hong Kong studied 69 strains of quinolone-resistant Neisseria gonorrhoeae taken from patients who did not respond to treatment with ofloxacin. Two antigens, Bop and Bpy, were found to be most common in quinolone-resistant gonorrhea. Ages of patients ranged from early adolescence to over 60, with the highest percentage in the 30-39 year age group. Cases of quinolone-resistant strains of gonorrhea may be increasing in southeast Asia. Sexually transmitted disease clinics should be aware of quinolone resistance in order to prevent the further spread of gonorrhea. N. gonorrhoeae may be successfully treated with spectinomycin and ceftriaxone.

Physiological aspects, Drug resistance, Quinolones

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Molecular epidemiology of infections with Neisseria gonorrhoeae among visitors to a sexually transmitted diseases clinic

Article Abstract:

Sexual preferences, antibiotic use, and ethnicity appear to be associated with specific gonorrhea strains variably resistant to standard treatment medications. Gonorrhea cell samples from 131 infected Dutch males were analyzed for bacterial strain and resistance to tetracycline and penicillin. The IB-1 strain was identified most frequently, particularly among those using prostitutes or having intercourse outside a committed relationship. Homosexual patients most frequently carried the IB-2 and IB-6 strains. Many patients carrying resistant strains had used antibiotics or were from Morocco or Surinam.

Analysis, Testing, Gay men, Microbial sensitivity tests

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Antimicrobial susceptibility and types of Neisseria gonorrhoeae in Greece: data for the period 1990 to 1993

Article Abstract:

It appears that a significant percentage of the gonorrhea infections in Greece are genetically resistant to many traditional medications. Researchers analyzed gonorrhea samples collected between 1990 and 1993 from 263 infected patients according to subtype and resistance to antibiotics and fluoroquinolones. Nineteen percent of the samples were genetically resistant to erythromycin, 18.5% to penicillin, 16% to chloramphenicol, and 12.5% to tetracycline. Many of the changing gonorrhea strain types were acquired out of the country.

Greece

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