Reactivation of genital herpes simplex virus type 2 infection in asymptomatic seropositive persons

Article Abstract:

Many patients infected with genital herpes can transmit the virus to another person even if they have no visible lesions or any other symptoms. Researchers tested genital fluids from 143 people whose blood tested positive for herpes simplex virus 2 (HSV-2). Ninety had symptoms of genital herpes and 53 did not. Three percent of both groups were shedding the virus in genital fluids. Sixty-two percent of the asymptomatic patients subsequently developed genital herpes lesions.

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Effect of Condoms on Reducing the Transmission of Herpes Simplex Virus Type 2 From Men to Women

Article Abstract:

Condoms can reduce the transmission of herpes virus 2, which causes genital herpes. Couples should also avoid sexual intercourse if one of the partners has herpes sores on their genitals.

Usage, Prevention, Condoms

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Virologic characteristics of subclinical and symptomatic genital herpes infections

Article Abstract:

Women with a history of genital herpes often release the virus from their genital tract and rectum even when they do not have any visible symptoms of infection. A total of 110 women with herpes simplex virus (HSV) infection entered a study for a median of 105 days. They kept diaries of visible genital sores, took samples from the vulva, cervix, and rectum with a swab, and visited a clinic every four to six weeks. On at least one day when sores were not visible, swab cultures contained the virus in 55% of the women with HSV-2, 52% with HSV-1 and HSV-2, and in 29% of the women with just HSV-1. On 32% of the days when virus was detected, there were no visible sores. This viral release without symptoms was more common in women who had been infected in the previous year and in women who had frequent recurrences of infection. Women with HSV-2 infections may be likely to release and transmit the virus to sexual partners even when they do not have sores.

Physiological aspects

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