Redefining lipodystrophy syndrome: Risks and impact on clinical decision making

Article Abstract:

Multivariate analysis is done to elucidate the relative contribution of risk factors of drug, disease, and host to fat redistribution, large epidemiologic studies in case of lipodystrophy syndrome. The results suggest that impairment to adipocyte differentiation, impairment to adipokine regulation, unopposed production of proinflammatory cytokines, dysregulation of 11-beta-hydroxysteroid dehydrogenase, and mitochondrial toxicity may play a role in diagnosis.

Analysis, Diagnosis, Multivariate analysis, Fat cells, Adipocytes

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Lipodystrophy and dyslipidemia among patients taking first-line, World Health Organization-recommended highly active antiretroviral therapy regimens in western India

Article Abstract:

The prevalence of lipodystrophy, dyslipidemia, and hyperglycemia among HIV-infected patients taking long term, first-line, World Health Organization (WHO) recommended generic highly active antiretroviral therapy (HAART) regimens in western India is determined. The study demonstrates a high prevalence of morphologic and metabolic complications among patients taking WHO-recommended generic HAART regimens.

India, Usage, World Health Organization, Hyperglycemia

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Adherence to antiretroviral therapy in patients receiving free treatment from a government hospital in Blantyre, Malawi

Article Abstract:

A study conducted to compare measures of adherence to antiretroviral therapy (ART) in HIV-positive adults receiving free treatment from a public hospital in Malawi recommend a requirement of improved methods to detect nonadherence in developing countries and validation of MC data with drug levels and virologic outcome.

Malawi, Evaluation, Hospitals, Public, Public hospitals, Clinical report

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