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Reduction of serum cholesterol with sitostanol-ester margarine in a mildly hypercholesterolemic population

Article Abstract:

Consumption of sitostanol-ester margarine as a portion of dietary fat may help reduce levels of blood cholesterol and low-density lipoprotein (LDL) cholesterol. Of 153 people with serum cholesterol levels of at least 216 milligrams per deciliter, 51 consumed margarine without sitostanol, and 102 consumed margarine with sitostanol-ester. In the latter group, 51 reduced their sitostanol intake from 3 grams a day to 2 grams a day after six months. Consumption of sitostanol-ester margarine led to a decrease in cholesterol levels by 7.4% after six months and 10.2% after a year; and a decrease in LDL cholesterol by 10.4% after six months and 14.1% after a year. Sitostanol-ester margarine also decreased levels of serum campesterol, which suggests a decrease in cholesterol absorption. High-density lipoprotein cholesterol and triglyceride levels were did not change. Participants reported no side effects and were able to distinguish between the margarines in a taste test but expressed no preference.

Author: Vartiainen, Erkki, Miettinen, Tatu A., Puska, Pekka, Gylling, Helena, Vanhanen, Hannu
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1995
Margarine, Sterols

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Twenty-year dynamics of serum cholesterol levels in the middle-aged population of Eastern Finland

Article Abstract:

Changes in diet and the time period a person was born in appear to significantly affect cholesterol levels. A total of 17,542 women and 16,711 men aged 25 to 64 years were interviewed and evaluated at five-year intervals between 1972 and 1992. Cholesterol levels did not significantly change over time among groups born within the same five-year time periods. Overall, cholesterol levels decreased during the study period for both men and women coinciding with a decrease in reported saturated fat in the participants' diet. Cholesterol levels were higher in older men and women.

Author: Vartiainen, Erkki, Tuomilehto, Jaakko, Puska, Pekka, Jousilahti, Pekka
Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1996
Physiological aspects, Dietary fat, Fins, Fins (Anatomy)

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Identifying Russian and Finnish adolescents' problem behaviours

Article Abstract:

Using a cross-cultural study, the problem behaviors of adolescents in Russia and Finland are compared in order to formulate effective health promoting methods.

Author: Vartiainen, Erkki, Puska, Pekka, Tossavainen, Kerttu, Kemppainen, Ulla, Jokela, Veikko, Pantelejev, Vladimir, Uhanov, Mihail
Publisher: Emerald Group Publishing, Ltd.
Publication Name: Health Education
Subject: Health
ISSN: 0965-4283
Year: 2007
Finland, Russia, Methods, Comparative analysis, Health promotion, Behaviour problems, Behavior problems, Adolescent behaviour, Adolescent behavior

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Subjects list: Health aspects, Blood cholesterol
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