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Reduction of sympathetic hyperactivity by enalapril in patients with chronic renal failure

Article Abstract:

ACE inhibitors may lower the risk of heart disease in patients with kidney failure by reducing the activity of the sympathetic nervous system. Increased sympathetic nerve activity can cause high blood pressure. Researchers directly measured sympathetic nerve activity in the muscles of 14 patients with hypertension, kidney failure and increased sympathetic nerve activity before and after they received the ACE inhibitor enalapril. Enalapril lowered blood pressure and also reduced sympathetic nerve activity.

Author: Ligtenberg, Gerry, Blankestijn, Peter J., Oey, P. Liam, Klein, Inge H.H., Dijkhorst-Oei, Lioe-Ting, Boomsma, Frans, Wieneke, George H., Huffelen, Alexander C. van, Koomans, Hein A.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1999
Blood pressure, Nervous system, Sympathetic, Sympathetic nervous system, Enalapril

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Effect of growth hormone treatment on adult height of children with idiopathic short stature

Article Abstract:

Treating short children with growth hormone for long periods of time will cause them to grow slightly taller than children of normal height. Researchers followed 121 short children who were treated with growth hormone for 2 to 10 years. Eighty achieved an adult height and were about 3.5 inches taller on average than children who were not treated. They were also an average of 2 inches taller than children of normal height.

Author: Attie, Kenneth M., Hintz, Raymond L., Baptista, Joyce, Roche, Alex
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1999
Health aspects, Care and treatment, Stature, Short, Short stature

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Effect of growth hormone treatment on the adult height of children with chronic renal failure

Article Abstract:

Growth hormone treatment of short children with chronic kidney problems appears to stimulate growth and lead to normal adult height, according to a study of 38 children of pre-puberty age. The mean final heights were 1.6 and 2.1 cm below normal adult height in hormone-treated and untreated children respectively.

Author: Haffner, Dieter, Schaefer, Franz, Nissel, Richard, Wuhl, Elke, Tonshoff, Burkhard, Mehls, Otto
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
United States, Germany, Statistical Data Included, Dwarfism

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Subjects list: Physiological aspects, Drug therapy, Chronic kidney failure, Children, Growth, Somatotropin
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