Relation between human T-lymphotropic virus type I and neurologic diseases in Panama: 1985-1990
Article Abstract:
A condition of muscle spasms and mild paralysis in the legs may indicate infection with the human T-cell lymphotropic virus type I (HTLV-I). Retroviruses, including HTLV-I, have been thought to cause some diseases of the nervous system. Researchers in Panama determined the rate of HTLV infection among hospital patients with neurologic disease. Out of 322 patients with neurologic disease, 17 were HTLV-I positive and two were positive for HTLV-II. Thirteen of 23 patients with muscle spasms and mild paralysis of the legs were HTLV-I positive. A few patients with multiple sclerosis and cerebellar syndrome had antibodies to HTLV-I. HTLV-I and HTLV-II may be native diseases in the Caribbean region and Panama.
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1995
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Questions on the evolution of primate T-lymphotropic viruses raised by molecular and epidemiological studies of divergent strains
Article Abstract:
The evolution of primate T-lymphotropic viruses (PTLV) is discussed. The term PTLV is used to describe both human T-lymphotropic virus (HTLV) and its counterpart in monkeys, simian T-lymphotropic virus (STLV). Many subtypes of HTLV are closely related to a similar STLV subtype. STLV-I has been found in many Old World monkeys and apes, but not in New World monkeys. This indicates that the virus originated after these monkeys diverged. Its counterpart in humans is HTLV-I, which is widespread. The two viruses probably crossed species many times in their evolution. A new STLV has been discovered in hamadryas baboons.
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1996
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The phylogeny and molecular epidemiology of human T-cell lymphotropic virus type II
Article Abstract:
There appear to be seven subtypes of human T-cell lymphotropic virus type II (HTLV-II). An assay using restriction fragment length polymorphism (RFLP) was used to determine the different HTLV-II subtypes in different population groups. HTLV-IIa was further subtyped into types A-1, A-II and A-III. HTLV-IIb was further subtyped into types B-I, B-II, B-III and B-IV. B-I and B-II was prevalent in intravenous drug addicts and B-III was found in many Indian populations. A-III was found in non-Indian populations in the US and Europe. A-II and B-IV were found primarily in Central and South America.
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1996
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