Differentially expressed genes regulated by acute distention in amniotic epithelial (WISH) cells

Article Abstract:

Distention of fetal membranes stimulates the expression of genes that produce interleukin-8 and pre-B-cell colony-enhancing factor. Fetal membranes become distended as the fetus grows.

Brief Article

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Differentially expressed genes regulated by acute distention in vitro

Article Abstract:

Three genes have been identified that are activated when fetal membranes become distended. The membranes become distended as the fetus grows.

Genetic aspects

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Relaxin causes proliferation of human amniotic epithelium by stimulation of insulin-like growth factor-II

Article Abstract:

A protein called relaxin appears to stimulate the growth of fetal membranes, according to a study of fetal membrane cell cultures. It does this by stimulating the production of insulin-like growth factor-II. Researchers are focusing on fetal growth because unborn babies that are too small or too large are more likely to be born prematurely.

Relaxin

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