Repeated coronary artery spasm in a young woman with the eosinophilia-myalgia syndrome

Article Abstract:

A 37-year-old woman who had previously been diagnosed with eosinophilia-myalgia syndrome associated with the use of tryptophan was admitted to a hospital with chest pain. She had no history of heart disease or any risk factors for coronary artery disease. A coronary angiogram showed that her left anterior descending coronary artery was obstructed. Her symptoms resolved after she was given nitrates and a calcium channel blocker, but she experienced severe chest pain a few days later. A repeat angiogram showed that her left anterior coronary artery was now obstructed in another area. A biopsy sample from her heart showed deposits of eosinophil granule proteins in the heart muscle. Eosinophils are a type of white blood cell. The concentration of tryptophan in her blood was normal, and her eosinophil level was also normal. Deposition of eosinophil granule proteins in various tissues may be responsible for the symptoms of eosinophilia-myalgia syndrome.

Case studies, Coronary vasospasm, Eosinophilia-myalgia syndrome

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Ischemia during ambulatory monitoring as a prognostic indicator in patients with stable coronary artery disease

Article Abstract:

Testing designed to show poor circulation to areas of heart muscle does not appear to predict who is a risk for heart attacks in patients with stable coronary artery disease. Researchers followed 221 patients for an average of four years. All patients had stable coronary artery disease and had exercise tests with electrocardiograms to evaluate heart function. The results of testing did not predict who would have a heart attack, develop unstable angina, die of heart disease, or require a procedure to open blocked cardiac vessels.

Causes of, Prognosis, Coronary heart disease, Ischemia, Ambulatory electrocardiography

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Time to Reevaluate Risk Stratification Guidelines for Medically Supervised Exercise Training in Patients With Coronary Artery Disease

Article Abstract:

Exercise training needs to be made available to all 12 million cardiac patients who might benefit from it. Research has shown that supervised exercise training can lower mortality rates as well as health care costs. However, many patients don't have access to a medical center that offers supervised training. Several studies have shown that a home-based training program may be suitable for some patients. This would require frequent phone contact between the patients and their doctor.

Evaluation, Exercise therapy, Cardiac patients

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