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Replication-selective virotherapy for cancer: biological principles, risk management and future directions

Article Abstract:

Viral vectors and whole viruses offer some possibility of being used in conjunction with current treatments for cancer. Viral therapies require unique safety and regulatory issues yet include advantages such as no cross-resistance and the ability to destroy tumors with numerous mechanisms.

Author: Kirn, David, Martuza, Robert L., Zwiebel, James
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
Research, Medical virology

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Biological drug duo delivers one-two tumor punch

Article Abstract:

Interleukin (IL)-2 has become the only established immunotherapy approved by the US food and Drug Administration for the treatment of refractory melanoma and renal cancer. The results IL-2 are obtained and the causes associated with it are examined.

Author: Mier, James W., Sosman, Jeffrey A.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2003
Government regulation, Licensing, certification and accreditation, Melanoma, Interleukin-2, Immunotherapy

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Smallpox, polio and now a cancer vaccine?

Article Abstract:

Dendritic cells have been used as a vaccine for matastatic renal cancer. These and renal carcinoma cells may be applicable to other types of cancer.

Author: Kufe, Donald W.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2000
Usage, Antigen presenting cells

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Subjects list: Care and treatment, Cancer, Cancer treatment
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