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Resistance to antimicrobial drugs - a worldwide calamity

Article Abstract:

Multidrug-resistant microorganisms are becoming more common worldwide. Drug resistant microorganisms have genetically mutated so that they are able to destroy or deactivate antimicrobial drugs. The introduction of penicillin in the 1940s started a new era of in medicine. Penicillin enabled many patients to survive who would have died in the past. The emergence of drug-resistance strains of bacteria created a new set of problems. These strains of bacteria have been spread throughout the world by an increasing mobile population, and the development of new antimicrobial drugs has not kept pace with the emergence of new strains of drug resistant bacteria. The problem of drug-resistant bacteria is especially serious in developing countries. More effort needs to be focused on the responsible use of antimicrobial drugs in developing countries.

Author: Kunin, Calvin M.
Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1993
Column, Anti-infective agents

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Factors associated with the development of antibiotic-resistant bacteria

Article Abstract:

The use of the antibiotic vancomycin in hospitals is causing many bacteria to become resistant to it, according to a study of 126 intensive care units in 60 US hospitals. Specifically, a type of bacteria called enterococci is becoming resistant to this drug, and the drug-resistant enterococci are being found in intensive care units as well as in other parts of the hospital.

Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 2001
Enterococcus

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Determinants of vancomycin resistance and death in enterococcal bacteremia

Article Abstract:

Patients who are infected with enterococci that are resistant to the antibiotic vancomycin have a worse prognosis than patients infected with non-resistant strains. Enterococci are bacteria that normally live in the intestines, but they can cause serious infection if they spread to the bloodstream.

Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 2001
Prognosis, Enterococcal infections, Septicemia

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Subjects list: Health aspects, Causes of, Drug resistance in microorganisms, Microbial drug resistance, Vancomycin
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