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Rethinking electronic health records to better achieve quality and safety goals

Article Abstract:

Introduction of information technology needs to be approached as an iterative process of care improvement instead of a one-time insertion of an information system into established practice. Information technology supports a family of technological methodologies, each with unique mechanisms of action, benefits and side effects, thus a staged method to turning direct access by patients to their health information into more effective care is presented.

Author: Stead, William W.
Publisher: Annual Reviews, Inc.
Publication Name: Annual Review of Medicine
Subject: Health
ISSN: 0066-4219
Year: 2007
Product quality, Methods, Usage, Quality management, Company systems management, Information management, Medical records, Patients, Patient care, Medical technology, Medical laboratory technology

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The drug development crisis: Efficiency and safety

Article Abstract:

Technologic methods for improving drug development efficiency are analyzed, which comprises high-content cell screening, expression profiling, mass spectroscopy, mouse models of disease, and post-launch screening program that allows investigation of adverse drug effects. Findings reveal that implementation of these new technologies assures improved performance in drug development and safety.

Author: Caskey, C. Thomas
Publisher: Annual Reviews, Inc.
Publication Name: Annual Review of Medicine
Subject: Health
ISSN: 0066-4219
Year: 2007
Product development, Pharmaceutical preparations, Market Research & Product Development, Evaluation, Safety and security measures, Pharmaceutical industry, Time to market

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Idiosyncratic toxicity: A convergence of risk factors

Article Abstract:

Studies reveal that idiosyncratic toxicities are normally not observed until a drug has been on the market and has gained broad exposure. It is observed that idiosyncratic toxicity can happen when a convergence of risk factors, including drug exposure, tips the risk-benefit balance away from benefit and toward risk.

Author: Ulrich, Roger G.
Publisher: Annual Reviews, Inc.
Publication Name: Annual Review of Medicine
Subject: Health
ISSN: 0066-4219
Year: 2007
Care and treatment, Causes of, Risk factors, Drug toxicity

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Subjects list: United States, Technology application, Drugs, Prevention, Adverse drug reactions
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