Rising incidence of hepatocellular carcinoma in the United States

Article Abstract:

The number of cases of hepatocellular carcinoma in the US has increased since 1980. Hepatocellular carcinoma is the most common type of liver cancer. Using three different databases of patient information, researchers discovered that the number of new cases of hepatocellular carcinoma rose from 1.4 per 100,000 people in 1980 to 2.4 per 100,000 people in 1995. Black men had the highest rates at 6 per 100,000 people. During the same time, mortality rates from hepatocellular carcinoma increased 41% and the hospitalization rate of affected patients increased 46%. The disease seems to strike younger patients than in the past.

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Prevention of primary liver cancer by immunization

Article Abstract:

Universal vaccination against hepatitis B may reduce the incidence of hepatocellular carcinoma. This is most common type of liver cancer and it has been linked to chronic infection with the hepatitis B virus. Hepatocellular carcinoma is common in Southeast Asia and several other developing countries. A 1997 study found that vaccination of all Taiwanese children in the 1980's led to a 50% reduction in the average annual incidence of hepatocellular carcinoma by 1994. The World Health Organization recommends universal hepatitis B vaccination of all infants.

Editorial, Prevention, Complications and side effects, Chronic active hepatitis

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Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children

Article Abstract:

Universal childhood vaccination against hepatitis B in Taiwan appears to have reduced the incidence of hepatocellular carcinoma. This is a type of liver cancer caused by chronic hepatitis B infection. An analysis of nationwide statistics on cancer reveal that the average annual incidence of hepatocellular carcinoma in children 6 to 14 years old was reduced by half between 1981-1986 and 1990-1994. Mortality rates from this disease also dropped during this period. In contrast, the rates of another type of childhood cancer, brain tumors, did not decrease.

Health aspects, Children, Vaccination of children, Vaccination, Taiwanese, Chinese (Taiwan)

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