Serologic evidence of previous Campylobacter jejuni infection in patients with the Guillain-Barre syndrome

Article Abstract:

Previous infection with Campylobacter jejuni (C. jejuni) is strongly associated with later development of Guillain-Barre syndrome. The syndrome involves the peripheral nervous system and symptoms include pain and weakness of the extremities. Guillain-Barre syndrome usually occurs within one to three weeks of an infection or immunization. The syndrome is often preceded by a diarrheal illness. C. jejuni is often associated with diarrheal illnesses. Blood samples were taken from 118 patients with Guillain-Barre syndrome within three weeks of the onset of symptoms and from 103 healthy individuals and patients with other diseases (the control group). Analysis for antibodies to the organism in patients' blood samples indicated that 36% of Guillain-Barre patients studied had evidence of previous C. jejuni infection. This association was strengthened as diagnostic criteria became more specific. Only 10% of the samples from the control group had evidence of C. jejuni infection.

Causes of, Guillain-Barre syndrome, Campylobacter infections, Campylobacteriosis

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Passover and plague

Article Abstract:

The observance of laws related to the festival of Passover is proposed as a control measure designed to diminish the risk for epidemic plagues to Jewish individuals and communities. The festival, which arguably embodied public health principles, required the complete removal of grain and food wastes from Jewish households. At the same time, the guideline minimized urban rat populations that carried the epidemics and allowed ancient Jews to escape and survive plagues.

Social aspects, Public health, Religious aspects, Plague, Passover

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Linking Helicobacter pylori to gastric cancer

Article Abstract:

Researchers have discovered a gene polymorphism for interleukin-1beta that may predispose people infected with Helicobacter pylori to get stomach cancer. This could explain why few people develop stomach cancer despite the fact that H. pylori is a common resident in the gastrointestinal tract.

Genetic aspects, Identification and classification, Genetic polymorphisms, Helicobacter infections, Stomach cancer

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