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Silent brain infarcts and the risk of dementia and cognitive decline

Article Abstract:

Healthy elderly people who have brain infarcts on an MRI scan have twice the risk of developing dementia in the future compared to those who do not, according to a study of 1,015 elderly people. The medical term infarct means that part of the body has not received enough blood and has begun to die. If it occurs in the brain, it is called a stroke. Some strokes may be so small they cause no symptoms.

Author: Hofman, Albert, Heijer, Tom den, Breteler, Monique M.B., Koudstaal, Peter J., Vermeer, Sarah E., Prins, Niels D.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2003
Brain infarction

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Total homocysteine and cognitive decline in a community-based sample of elderly subjects: The Rotterdam Study

Article Abstract:

Cognitive decline, major dementia symptom, as related to total homocysteine levels is discussed as seen in a community-based study of elderly subjects in The Netherlands. A relationship between cognitive decline and homocysteine seems plausible, based on biology, but no association was found in the study.

Author: Hofman, Albert, Launer, Lenore J., Breteler, Monique M.B., Lindemans, Jan, Bots, Michiel L., Kalmij , Sandra
Publisher: Johns Hopkins University Press
Publication Name: American Journal of Epidemiology
Subject: Health
ISSN: 0002-9262
Year: 1999
Netherlands, Psychological aspects, Aging, Statistical Data Included, Research, Mortality, Physiological aspects, Statistics, Epidemiological research, Cross sectional studies, Homocysteine

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Incidental findings on brain MRI in the general population

Article Abstract:

A study to examine the total number of cases of the disease like brain tumors, vascular abnormalities, in general population at a given time was conducted. Results concluded that most frequent incidental brain findings on MRI is brain infarcts, cerebral aneurysms and tumors.

Author: Hofman, Albert, Breteler, Monique M.B., Krestin, Gabriel P., Vernooij, Meike, Ikram, M. Arfan, Tanghe, Herve L., Vincent, Arnaud J.P.E., Niessen, Wiro J., van der Lugt, Aad
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
United States, Population, Evaluation, Diagnosis, Technology application, Magnetic resonance imaging, Brain tumors, Brain tumours, Clinical report

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Subjects list: Health aspects, Risk factors, Dementia
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