Stem cell therapy: Moving towards reality

Article Abstract:

The adult stem cells can be transplanted into children and fetuses with demonstrable improvement in limited situations such as with X-linked Severe Combined Immunodeficiency Disorder. Multiple decades of experience in fetal therapy have found that most situations are far more complex than originally thought and there is usually more than one successful strategy and educated guessing suggests that for different metabolic and anatomic pathology, different stem cell populations will be needed.

Care and treatment, Stem cells, Stem cell transplantation, Severe combined immunodeficiency

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First-trimester fetal reduction to a singleton infant or twins: Outcome in relation to the final number and karyotyping before reduction by transabdominal chorionic villus sampling

Article Abstract:

A study is conducted to evaluate fetal outcome and maternal complications of multifetal pregnancy reduction to a single fetus or twins, thus attempting to assess safety and efficacy of transabdominal chorionic villus sampling for karyotyping before fetal reduction. The outcome of multiple pregnancies that were reduced to a single fetus or twins was similar to that of nonreduced pregnancies.

Methods, Complications and side effects, Abortion, Pregnancy, Multiple, Multiple pregnancy

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Automated detection of rare fetal cells in maternal blood: eliminating the false-positive XY signals in XX pregnancies

Article Abstract:

A study to develop a new method to for the differentiation of XX signals from XY signals in maternal blood from women carrying XY fetuses is conducted. The results revealed that situ hybridization signals system allows for signal to noise separation, which is required for fetal cell methods to differentiate aneuploid from normal pregnancies.

Fetal tissues, Prenatal diagnosis, Cell hybridization

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