Survival and morbidity of extremely premature infants based on obstetric assessment of gestational age

Article Abstract:

Since treatment decisions regarding very-low-birth-weight infants are based on an assessment of the infant's prognosis, the information regarding likely outcomes of various conditions must be current and accurate. To learn more about the effects of current treatment approaches on neonatal survival and complications, the medical records of 141 live-born infants with birth weights of 1,600 grams (3.52 pounds) or less were studied. The infants had gestational ages of 24 to 29 weeks at birth. More than 80 percent of those with a gestational age greater than 26 weeks survived to discharge, and infants who weighed more than 700 grams had much improved survival rates compared with lighter babies. Only 20 percent of the neonates born with a gestational age of 24 weeks survived, while 94 percent of those born at 29 weeks survived. Extremely premature infants succumb most commonly to chronic lung disease or intraventricular hemorrhage (bleeding in the brain); these conditions occurred more frequently at lower gestational ages. In general, survival rates for these very-low-birth-weight infants have greatly improved in the last four to five years. The ultimate fate of many such infants, however, may include handicaps and learning disabilities. (Consumer Summary produced by Reliance Medical Information, Inc.)

Patient outcomes, Mortality, Prognosis, Birth weight, Low, Low birth weight, Infant mortality

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Antenatal sonographic findings in a case of intra-abdominal pulmonary sequestration

Article Abstract:

A fatal case of pulmonary sequestration within the abdomen, a rare type of congenital malformation caused when the lung tissue becomes disconnected from the bronchial tree and from the pulmonary veins, was detected in a 30-week old fetus by use of ultrasound. In an autopsy of the fetus, the condition was confirmed. If a routine ultrasound examination of a fetus reveals an abdominal mass, differential diagnosis should include testing for pulmonary sequestration, even though the disease is rare.

Infants (Newborn), Lung diseases, Neonatal diseases, Abdomen, Diagnosis, Ultrasonic, Diagnostic ultrasonography

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Anti-Co3 and severe hemolytic disease of the newborn

Article Abstract:

Hemolytic disease is a disruption of the integrity of red blood cell membranes causing the release of hemoglobin, the oxygen-carrying pigment of red blood cells. The disruption is caused by antibodies that destroy the blood cells. Treatments of hemolytic diseases in infants is reviewed. The antibody anti-Colton 3 is responsible for hemolysis in infants. Two such cases are described. Care and treatment of the disease is discussed.

Health aspects, Analysis, Autoantibodies, Hemolysis and hemolysins, Hemolysis, Blood transfusion, Erythroblastosis fetalis

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