Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma

Article Abstract:

Gastroesophageal reflux appears to increase the risk of a type of esophageal cancer called adenocarcinoma. Gastroesophageal reflux occurs when the contents of the stomach back up into the esophagus. Researchers analyzed the medical histories of 451 patients with esophageal adenocarcinoma, 167 patients with esophageal squamous cell carcinoma and 820 healthy people. People with a history of gastroesophageal reflux had over seven times the risk of esophageal adenocarcinoma and the risk among those with long-standing or severe gastroesophageal reflux was 43 times greater. There was no link between gastroesophageal reflux and esophageal squamous cell carcinoma.

Gastroesophageal reflux

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Blood transfusion and non-Hodgkin lymphoma: lack of association

Article Abstract:

Patients given blood transfusions do not seem to be at greater risk for developing non-Hodgkin's lymphoma. Transfusion histories between 1970 and 1983 were compared among 361 patients who later developed non-Hodgkin's lymphoma and 705 matched hospitalized patients. There was a similar percentage of patients in each group who had received transfusions. The risk for developing non-Hodgkin's lymphoma tended to be lower for patients who had received multiple transfusions with high concentrations of white blood cells.

Non-Hodgkin's lymphomas, Blood transfusion

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Association between Body Mass and Adenocarcinoma of the Esophagus and Gastric Cardia

Article Abstract:

Obesity may substantially increase the risk of adenocarcinoma of the esophagus. Researchers evaluated 451 patients with adenocarcinoma of the esophagus or gastric cardia, 167 patients with squamous-cell esophageal cancer, and 820 healthy people. Among the most obese, the prevalence of adenocarcinoma of the esophagus was 16 times the prevalence in the leanest patients. It is not known how obesity may influence the development of esophageal cancer.

Sweden, Obesity, Adenocarcinoma

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