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Targeting angiogenasis with a conjugate of HPMA copolymer and TNP-470

Article Abstract:

A conjugate of HMPA copolymer and TNP-470 is emerging as a new class of anticancer drugs. Thus, this new approach for targeting angiogenasis inhibitors specifically to the tumor vasculature may provide a new strategy for the rational design of cancer therapies.

Author: Fainaro, Roni Satchi, Puder, Mark, Tran, Hai T., Sampson, David A.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2004
Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Anticancer Drugs, Chemotherapeutic Drugs, Anticancer Immunostimulant Preps, Antineoplastic agents, Antimitotic agents, Angiogenesis inhibitors

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CpG motifs: the active ingredient in bacterial extracts?

Article Abstract:

The discovery of surgeon William B. Colley that, injecting them with Streptococcus pyogenes and Serratia Marcescens can cure cancer patients is described. Bacteria or Bacterial extracts acts as immune aviators that triggers specific receptors of immune cells

Author: Kreig, Arthur M.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2003
Usage, Streptococcus pyogenes, Medical research personnel, Medical researchers, Colley, William B.

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The antioxidant function of the p53 tumor suppressor

Article Abstract:

The antioxidant function of the p53 tumor suppressor is studied. The results provide a new paradigm for a nonrestrictive tumor suppressor function of p53 and highlight the potential importance of antioxidants in the prophylaxis and treatment of cancer.

Author: Sablina, Anna A., Budanov, Andrei V., Ilyinskaya, Galina V., Agapova, Larissa S., Kravchenko, Julia E., Chumakov, Peter M.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2005
Cancer, Tumor suppressor genes, Tumour suppressor genes

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Subjects list: Research, United States, Cancer treatment
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