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HMG-CoA Reductase Inhibitors and the Risk of Hip Fractures in Elderly Patients

Article Abstract:

A group of drugs called statins may lower the risk of bone fracture. Stains are used to treat high cholesterol levels. In a study of 1,222 people woh had a hip fracture and 4,888 who did not, the use of statins reduced the risk of bone fracture 71%. Animal studies have shown that statins increase bone formation and bone density.

Author: Wang, Philip S., Solomon, Daniel H., Mogun, Helen, Avorn, Jerry
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2000
Bones, Prevention, Fractures (Injuries), Fractures, Anticholesteremic agents

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Risk of death in elderly users of conventional vs. atypical antipsychotic medications

Article Abstract:

A retrospective cohort study involving 22,890 patients 65 years of age who had drug insurance benefits in Pennsylvania and who began receiving atypical antipsychotic medication between 1994 and 2003 is conducted. Results suggest that conventional antipsychotic medications are as likely as atypical agents to increase the risk of death among elderly persons and that conventional drugs should not be used to replace atypical agents discontinued in response to the FDA warning.

Author: Wang, Philip S., Solomon, Daniel H., Mogun, Helen, Avorn, Jerry, Fischer, Michael A., Schneeweiss, Sebastian, Brookhart, M. Alan
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
Science & research, Research, Drugs, Risk factors, Aged patients, Elderly patients, Antipsychotic drugs, Antipsychotic agents, Adverse drug reactions

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Telephone screening, outreach, and care management for depressed workers and impact on clinical and work productivity outcomes: a randomized controlled trial

Article Abstract:

The effects of a depression outreach-treatment program on workplace are evaluated. The program proves to be beneficial to both clinical and workplace outcomes by identifying depression and providing enhanced care for the same.

Author: Ludman, Evette J., Kessler, Ronald C., Wang, Philip S., Avorn, Jerry, Simon, Gregory E., Azocar, Francisca, McCulloch, Joyce, Petukhova, Maria Z.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2007
Health Care and Social Assistance, HEALTH SERVICES, Employee Health & Safety, Care and treatment, Methods, Evaluation, Occupational health and safety, Occupational safety and health, Diagnosis, Medical examination, Depression, Mental, Depression (Mood disorder), Medical screening, Health screening, Workers, Clinical report

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Subjects list: Health aspects, United States
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