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That oestrogen replacement for osteoporosis prevention should no longer be a bone of contention

Article Abstract:

Estrogen replacement therapy may be an effective method to prevent or decrease the progression of osteoporosis in post-menopausal women. Osteoporosis is a disorder characterized by bone mineral loss and an increased risk of fractures. Treatment with estrogen may increase the risk of endometrial cancer, or cancer of the lining of the uterus, in post-menopausal women. The use of progestogen in combination with estrogen decreases this risk significantly. Estrogen replacement therapy may also increase the risk of gallstone formation and possibly of breast cancer. Progestogen hormones may not protect against breast cancer. Treatment with progestogen may cause symptoms similar to those of premenstrual syndrome. Postmenopausal women may be advised to undergo dual energy x-ray absorptiometry to evaluate bone mineral loss. Women with decreased bone mineral density may choose to begin treatment with hormone replacement therapy.

Author: Palferman, T.G.
Publisher: British Medical Association
Publication Name: Annals of the Rheumatic Diseases
Subject: Health
ISSN: 0003-4967
Year: 1993
Care and treatment, Estrogen, Estrogens, Aged women, Elderly women

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Exercise in primary prevention of osteoporosis in women

Article Abstract:

Varied brief high impact bone loading exercise appears to improve bone health, particularly in postmenopausal women. Bone mineral density is a frequently used measurement for evaluating bone mass and predicting risk for bone breakage. Researchers presented evidence from studies that evaluated the effects of exercise on bone mineral density in premenopausal and postmenopausal women. Studies have shown that high impact aerobic exercise, such as jogging or fast walking, improves spinal bone mineral density by 1% in premenopausal women and by 7% in postmenopausal women. The spinal bone mineral density decreased in women not participating in an exercise program. Low impact exercise, such as swimming or routine walking, does not seem to significantly improve spinal bone mineral density. Studies have also shown that jumping in place improves the bone mineral density in the thigh bones.

Author: Bassey, E.J.
Publisher: British Medical Association
Publication Name: Annals of the Rheumatic Diseases
Subject: Health
ISSN: 0003-4967
Year: 1995
Aerobic exercises, Women's fitness

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Growth in infancy and bone mass in later life

Article Abstract:

There may be some indications in infancy what type of bone condition patterns will develop as the person ages. Body weight at one year of age and current bone density measurements, urinary collagen levels, and osteocalcin blood levels were analyzed among 224 men and 189 women aged 63 to 73 years. Body weight at one year was significantly associated with spinal bone content for men and spinal and hip bone content for women. There was no association between weight at one year and other measurements.

Author: Cooper, Cyrus, Barker, David, Eastell, Richard, Egger, Peter, Fall, Caroline, Hobbs, Richard
Publisher: British Medical Association
Publication Name: Annals of the Rheumatic Diseases
Subject: Health
ISSN: 0003-4967
Year: 1997
Measurement, Risk factors, Bone diseases, Infants, Growth, Body weight

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Subjects list: Health aspects, Prevention, Osteoporosis, Bones, Bone density
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