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Measurement of the urinary lactate:creatinine ratio for the early identification of newborn infants at risk for hypoxic-ischemic encephalopathy

Article Abstract:

A urinary lactate to creatinine ratio of 0.64 or higher seems to accurately predict which newborn infants exposed to low oxygen levels will develop brain damage. Low oxygen levels, a condition known as hypoxia, can cause a brain disorder called ischemic encephalopathy. In a study of 58 normal babies and 40 babies with hypoxia, a urinary lactate to creatinine ratio of 0.64 or higher within 6 hours of birth accurately identified 94% of the infants who would develop ischemic encephalopathy.

Author: Huang, Chao-Ching, Wang, Shan-Tair, Chang, Ying-Chao, Lin, Kung-Ping, Wu, Pei-Lin
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1999
Statistical Data Included, Diagnosis, Complications and side effects, Hypoxia, Anoxia, Lactic acid, Creatinine, Encephalopathy

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Risk factors for relapse in health care professionals with substance use disorders

Article Abstract:

A study was carried out on chemically dependent health care professionals who were using a major opioid such as fentanyl, sufentanil, morphine, and meperidine as a drug as there was a higher risk of relapse among them. The results showed that the health care professionals who used opioid are at a higher risk of relapse of the disease.

Author: Hornbein, Thomas F., Domino, Karen B., Polissar, Nayak L., Renner, Ginger, Johnson, Jilda, Alberti, Scott, Hankes, Lynn
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
United States, Pharmaceutical Preparation Manufacturing, Narcotic Analgesic Preparations, Usage, Risk factors, Diseases, Opioids, Recurrence (Disease)

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