The efficacy of an intraoral fluoride-releasing system in irradiated head and neck cancer patients: a preliminary study

Article Abstract:

A fluoride-releasing device may prevent tooth cavities as effectively as the daily application of fluoride gel in patients with dry mouths from radiation treatment. Irradiation of the head and neck can suppress salivation, markedly increasing the risk of dental caries. Dentists compared fluoride gel, the standard preventive treatment, with a tiny device containing a fluoride pellet and bonded to a tooth, in 23 cancer patients. In six months, only one patient in each treatment group developed cavities. Eighty-five percent of patients preferred the fluoride delivery device.

Prevention, Dental caries, Radiotherapy, Head and neck cancer, Dental prophylaxis, Sodium fluoride

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Analgesic efficacy and safety of an intraoral lidocaine patch

Article Abstract:

Adhesive patches containing anesthetic may be an effective way of delivering anesthesia within the mouth before dental procedures. Researchers tested the effectiveness of 10% and 20% adhesive lidocaine patches in reducing mouth pain before needle injection in the mouths of 100 patients. Patients receiving either the 10% or 20% concentration lidocaine patches reported less pain from needlesticks than patients receiving placebo patches, and anesthesia was perceived 2.5 to 5 minutes after patch placement. No drug reactions were observed.

Evaluation, Transdermal medication, Transdermal drug delivery systems, Injections, Hypodermic, Subcutaneous injections, Lidocaine

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Interactions involving antibiotics

Article Abstract:

Dentists should be aware of potential drug interactions when they give patients antibiotics. Most dentists don't use antibiotics very often, but antibiotics can interact dangerously with other drugs. Some antibiotics block the metabolism of other drugs. Interactions can occur between some antibiotics and other types of drugs as well as between two different antibiotics. There is little evidence that antibiotics can interfere with oral contraceptives.

Analysis, Antibiotics, Drug interactions

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