Gene variants explain patient differences in antiepileptic drug responses

Article Abstract:

Particular genetic variations could explain variation in response of patients with epilepsy to antiepileptic drugs such as the differences in the doses of drugs required to control seizures. Two genes were studied, where one variant was CYP2C9 and the other was SCN1A that might influence response to carbamazepine and phenytoin, the first-line antiepileptic drugs.

Drug therapy, Genetic variation

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The new antiepileptic drugs

Article Abstract:

The general practitioner has been familiarized with the appropriate roles and effective uses of the latest antiepileptic drugs in specific clinical conditions. The various uses and effects have been highlighted.

Management dynamics, Hypertension, Practice, Physicians (General practice), General practitioners, Cookery for hypertensives

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The new antiepileptic drugs

Article Abstract:

Data is provided on the efficacy and tolerability of the new antiepileptic drugs. The results of experiments done on theses drugs are presented.

Gabapentin, Felbamate

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