The role of diacylglycerol as a modulator of oxytocin-stimulated phasic contractions in myometrium from pregnant and nonpregnant rats

Article Abstract:

Diacylglycerol appears to be involved in the phosphatidylinositol-signaling pathway by which oxytocin activates protein kinase C. Protein kinase C in turn inhibits uterine contractions.

Myometrium, Oxytocin

---

The mechanisms underlying the stimulatory effects of thrombin on myometrial smooth muscle

Article Abstract:

The enzyme thrombin can stimulate the uterus to contract and these contractions are as strong as those induced by oxytocin and prostaglandins. Thrombin is involved in blood clotting. This could explain why premature separation of the placenta, accompanied by intrauterine bleeding, causes the uterus to contract.

Abruptio placentae, Placental abruption

---

Effects of thrombin on myometrial contractions in vitro and in vivo

Article Abstract:

Thrombin appears to make the uterus contract, which could explain why uterine bleeding can cause miscarriage and premature labor. Thrombin is the enzyme in blood that initiates blood clotting, but it may also have other physiological effects.

Similar abstracts:

• Abstracts: Degranulation of uterine mast cell modifies contractility of isolated myometrium from pregnant women. The effects of pregnancy and smooth muscle contractility on cervical distensibility in the rat
• Abstracts: Role of nucleotide cyclases in the inhibition of pregnant rat uterine contractions by the openers of potassium channels
• Abstracts: Antiphospholipid antibodies in women at risk for preeclampsia

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.