Transplantation pioneer predicts successful xenotransplantation soon
Article Abstract:
Xenotransplantation is the transplantation of organs or tissues between different species. In Jun 1992 and Jan 1993, two women received baboon livers. Although neither patient survived, Thomas E. Starzl, a leading surgeon in the field of xenotransplantation, says these transplants may be feasible by 1994. A key factor in the success of any transplant is the migration of cells from the host into the transplanted organ and the migration of cells from the transplanted organ throughout the host. Essentially, successful organ transplants are also mini-bone marrow transplants. Using this knowledge, future organ recipients may also receive bone marrow from the donor to boost their immune system and lessen the chance of organ rejection. Although other researchers are skeptical, successful xenotransplantation could offer hope to the thousands of people on waiting lists for transplants.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1993
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Unique aspects of heart and lung transplantation exhibited in the 'domino-donor' operation
Article Abstract:
The case is described of the first 'domino-donor' operation performed, in May 1987, in the United States. A 28-year-old man with cystic fibrosis and end-stage lung disease received the heart and lungs of an anonymous donor and donated his heart to another man with ischemic cardiomyopathy. The operative procedures involved were similar to previously described techniques, with some modifications to boost the technical ease of each operation. In order to procure and transplant the multiple organs over a significant distance, the technique of cardiopulmonary bypass and profound hypothermia was employed. Similar domino-donor operations that have been performed since are surveyed, and key considerations in determining when to undertake this procedure are discussed.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1989
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General surgery
Article Abstract:
About 50% of all U.S. surgery is performed in an ambulatory setting, at considerable cost savings. Over 3.5 million endoscopic procedures were performed in 1995 in ambulatory units. Endovascular graft placement is being used to treat aneurysms and atherosclerosis. Graft usage was successful in eight of 10 patients in a study. Powderless gloves should be used to avoid contamination of surgical wounds. Research regarding scarless wound repair in fetuses is under way. The use of swine hepatocytes to create a support system before liver transplantation is deemed safe and effective.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1995
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