Treating patients with severe sepsis

Article Abstract:

Mortality rates from sepsis are dropping even though no treatment has proven effective. Sepsis is a system-wide failure of organ function that is usually caused by an infection. Half a million patients in the US develop sepsis every year, and about half will die. Death is often due to organ failure. If organ failure can be prevented, so can deaths even though no treatment is available for sepsis. Basic supportive treatment includes enteral nutrition and the prevention of additional infections, stress ulcers and complications of bed rest. Many patients with sepsis may have other diseases that contribute to their death.

Patient outcomes, Mortality, Critically ill, Septicemia

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Noninvasive ventilation-Don't push too hard

Article Abstract:

Noninvasive ventilation can be used as an adjunctive therapy and can be applied before intubation or after extubation. Randomized and controlled trials prove the use of noninvasive ventilation to prevent the need for endotracheal intubation in immunosuppressed patients who have biolateral infiltrates as well those who are recovering from lung resection.

United States, Usage, Artificial respiration, Mechanical ventilation

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Dysfunction of endothelial protein C activation in severe meningococcal sepsis

Article Abstract:

Protein C is not activated as it normally should be in patients with severe meningococcal infection. This may explain why these patients develop abnormal blood clots, since protein C is a naturally occurring anticoagulant in the body.

Meningococcal infections, Protein C deficiency

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