Noninvasive Ventilation for Treatment of Acute Respiratory Failure in Patients Undergoing Solid Organ Transplantation: A Randomized Trial

Article Abstract:

Some patients in respiratory failure can be treated with noninvasive ventilation (NIV). This involves giving the patient air through a face mask rather than via a mechanical ventilator. Patients on mechanical ventilators must have a tube placed down their throat, which can lead to pneumonia. Researchers randomly assigned 40 organ transplant recipients in respiratory failure to receive NIV or standard mechanical ventilation. Those receiving NIV were more likely to have improved blood gases, fewer complications, and shorter stays in the intensive care unit. Fewer patients receiving NIV died during the treatment.

Innovations, Organ transplant recipients

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Treatment of Acute Hypoxemic Nonhypercapnic Respiratory Insufficiency With Continuous Positive Airway Pressure Delivered by a Face Mask: A Randomized Controlled Trial

Article Abstract:

Continuous positive airway pressure (CPAP) delivered by a face mask does not improve the outcome of patients with respiratory insufficiency caused by lung injury. This was the conclusion of a study of 123 patients who receiveD oxygen therapy alone or oxygen therapy plus CPAP. CPAP is less invasive than a ventilator.

Europe, Respiratory insufficiency

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A comparison of noninvasive positive-pressure ventilation and conventional mechanical ventilation in patients with acute respiratory failure

Article Abstract:

Noninvasive positive-pressure ventilation appears to be more effective in treating patients with acute respiratory failure than traditional mechanical ventilation and has fewer adverse effects. This technique involves giving patients oxygen and other gases through a face mask rather than putting them on a ventilator. Researchers compared the two techniques in a study of 32 patients receiving the noninvasive method and 32 on traditional ventilators. More patients in the noninvasive group survived to be discharged from the hospital and had fewer complications. Their hospital stays were also shorter.

Methods, Acute respiratory distress syndrome, Adult respiratory distress syndrome

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