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Treatment of hypercholesterolemia in women: equality, effectiveness, and extrapolation of evidence

Article Abstract:

Women with elevated cholesterol levels appear to benefit as much as men if not more so from cholesterol-lowering drugs. However, research is needed to find out why so many men and women are receiving inadequate doses of the drugs. A 1997 study of 2,763 postmenopausal women with elevated cholesterol levels found that 91% had cholesterol levels above those considered normal. This has also been documented in men, so this is not a result of discrimination. Studies have shown that women with coronary heart disease have the same or worse prognosis as men and therefore should receive adequate drug treatment.

Author: Pearson, Thomas A., Myerson, Merle
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1997
Drug therapy, Postmenopausal women, Hypercholesterolemia

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Therapy for Fracture Prevention

Article Abstract:

There are drugs that can lower the risk of bone fracture in postmenopausal women with osteoporosis but they are best reserved for those at high risk of fracture. A 1999 study documented the effectiveness of the drug raloxifene in reducing the risk of vertebrae fractures in women with osteoporosis. This drug has the beneficial actions of estrogen without its adverse effects. However, raloxifene did not affect the risk of non-spine fractures. Drugs such as this only seem to benefit women at high risk of bone fractures. A woman's risk of bone fracture can be assessed by measuring her bone density.

Author: McClung, Michael R.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1999
Statistical Data Included, Evaluation, Complications and side effects, Osteoporosis, Raloxifene

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Use of Statins and Risk of Fractures

Article Abstract:

A class of cholesterol-lowering drugs called statins do not appear to lower the risk of bone fractures. This was the conclusion of researchers who studied 81,880 patients who had experienced a bone fracture and 81,880 patients who had not.

Author: Cooper, Cyrus, Staa, Tjeerd-Pieter van, Wegman, Sebastiaan, Vries, Frank de, Leufkens, Bert
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
Bones

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Subjects list: Health aspects, Editorial, Anticholesteremic agents, Prevention, Fractures (Injuries), Fractures
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