Umbilical cord ulceration and intestinal atresia: a new association?

Article Abstract:

Three case histories are presented of infants born with intestinal atresia (partial closure of the intestinal tract) and signs of ulceration (sores) of the umbilical cord. The deliveries, complications, pathologic findings, and results from evaluating the placentas are described. One infant developed asthma (the mother was an asthma patient); the second had cardiac problems, and the third was stillborn. In all cases, ulcerations were seen on the umbilical cords, segments of the digestive tracts were not open, and hemorrhage had occurred in utero from the ulcers. The ulcers are described, which were probably the result of injury, but the injurious agent was not identified. Three hypotheses are presented that could associate the findings of umbilical cord ulceration and intestinal atresia: abnormal reactivity of blood vessels, which could lead to spasm of the vessels and reduction in the levels of available oxygen, harming tissue; gastric reflux, in which backwards flow of stomach contents could cause an ulcer; or epithelial abnormalities, affecting the cells that line both the blood vessels and the intestinal tract. Such cases are rare, but it is likely that the poor outcome in these cases resulted from a failure to recognize the possibility of hemorrhage. This should also be considered in cases where bowel atresia is diagnosed prenatally. (Consumer Summary produced by Reliance Medical Information, Inc.)

Abnormalities, Diagnosis, Physiological aspects, Birth defects, Umbilical cord

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Impact of hospital and surgeon volumes on outcomes following pelvic reconstructive surgery in the United States

Article Abstract:

A retrospective cohort study was undertaken to examine the effect of hospital and surgeon volumes on outcomes following pelvic reconstructive or urogynecologic surgery in the US. Results suggested that differences in hospital and surgeon volumes of urogynecologic procedures might contribute to variations in mortality and morbidity risks, although these procedures are usually associated with low overall mortality risks.

United States, Mortality, Risk factors, Pelvic inflammatory disease

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Pregnancies after reconstructive surgery for congenital cervicovaginal atresia

Article Abstract:

Doctors describe a surgical operation to create a cervix and vagina in women with a functioning uterus but no cervical opening and no vagina. Of 18 women treated between the ages of 12 and 20, all began menstruating normally and two gave birth to healthy babies.

Surgery, Genital diseases, Female, Female genital diseases

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