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Unraveling hepatitis B virus infection of mice and men (and woodchucks and ducks)

Article Abstract:

It has been difficult to study chronic hepatitis B infection because the virus has a limited host range. However, woodchucks are naturally infected by a very similar virus, and they develop chronic liver disease and liver cancer just as humans infected by hepatitis B virus do.

Author: Menne, Stephen, Tennant, Bud C.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 1999
Research, Hepatitis B

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Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans

Article Abstract:

The authors report on investigation as to the reason for depletion of T-cells in persons infected with HIV-1 virus. They attribute this occurrence to a combination of shortened survival time of the cells along with a lack of increase in T-cell production.

Author: Schmidt, D., Hellerstein, M., Hanley, M.B., Cesar, D., Siler, S., Papageorgopoulos, C., Wieder, E., Hoh, R., Neese, R., Macallan, D., Deeks, S., McCune, J.M.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 1999
Physiological aspects, Development and progression, HIV infection, HIV infections, T cells

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