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Varicella vaccination: evidence for frequent reactivation of the vaccine strain in healthy children

Article Abstract:

The Oka chickenpox vaccine may reactivate inside the body, boosting the production of antibodies against the wild-type virus. In a study of 4,631 vaccinated children followed for 4 years, the rate of reactivation and immunological boosting exceeded the rate of exposure to wild-type varicella.

Author: Krause, Philip R., Klinman, Dennis M.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2000
Chickenpox vaccine, Chickenpox vaccines

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Unraveling the strands of HIVs web

Article Abstract:

The author contends that accepted theory which says that HIV destroys CD4 cells which need to be restored in huge quantities, but the ablity gradually diminishes is not probable. He suggests that shortened life span of CD4 cells with no change in production of new ones is more likely.

Author: Pantaleo, Giuseppe
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 1999
Development and progression, HIV infection, HIV infections

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The role of CD4+ lymphocytes in the susceptibility of mice to stress-induced reactivation of experimental colitis

Article Abstract:

Stress can reactivate colitis in mice and CD4+ T cells appear to be involved. Stress reduces levels of mucin and increases mucosal permeability, which would allow sensitizing agents to enter the mucosa more easily.

Author: Qiu, B.S., Vallance, B.A., Blennerhassett, P.A., Collins, S.M.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 1999
Risk factors, Stress (Psychology), Colitis

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Subjects list: Physiological aspects, CD4 lymphocytes
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