How we describe competitive antagonists: three questions of usage

Article Abstract:

Various incorrect terms have been used to replace three pharmacological terms that are descriptive of competitive antagonists. These erroneous terms do not fully identify the term they pertain. One of these terms is the pAx value which is erroneously interchanged with log K(sub B). The word noncompetitive is sometimes used to describe competitive interactions. Similarly, the words affinity, equilibrium and dissociation constants have been used describe each other even though their meaning are fundamentally different.

Antimetabolites

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TiPS Receptor and Ion Channel Nomenclature Supplement 1997

Article Abstract:

The Trends in Pharmacological Sciences (TiPS) journal's TiPS Receptor and Ion Channel Nomenclature Supplement 1997 was written John A. Peters and Steve P.H. Alexander. The supplement, which is the most comprehensive edition published by TiPS, features the nomenclature used in the journal. It offers information from Subcommittees of the International Union of Pharmacology Committee on Drug Classification and Receptor Nomenclature.

Names

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2000 Receptor and Ion Channel Nomenclature Supplement

Article Abstract:

A series of tables is presented on more than 50 new classes of receptors and ion channels, along with structural information for 99% of them. Receptors include chemokine, leukotriene, melanocortin, and vanilloid; ion channels include acid-sensing, or proton-gated, calcium, and potassium.

United States, Illustration, Ion channels, Pharmaceutical research

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