Modulation of PAI-1 and tPA activity and thrombolytic effects of corilagin

Article Abstract:

A study was conducted on the thrombolytic effect of corilagin from a Chinese herbal plant, as well as its effect on carotid artery patency status. Tests carried out on rats and rabbits reveal that corilagin inhibited PAI-1 activity and increased tPA activity, and this property of corilagin is assumed to be responsible for the thrombolytic effect.

Tissue plasminogen activator, Phyllanthus

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Effects of quercetin treatment on vascular function in deoxycorticosterone acetate-salt hypertensive rats: comparative study with verapamil

Article Abstract:

A study was conducted to investigate the effects of chronic oral administration of a daily dose of the flavonoid quercetin on systolic blood pressure (SBP) and vascular alteration in deoxycorticosterone acetate (DOCA)-salt hypertensive rats. The effects of quercetin are compared with those exerted by the antihypertensive drug, verapamil.

Quercetin, Verapamil

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Quantitative analysis of strychnine and brucine in Strychnos nux-vomica using 1H-NMR

Article Abstract:

A quantitative analysis using 1H-NMR (Q-NMR) has been developed for the determination of strychnine and brucine in Strychnos nux-vomica seeds and stems. This method has significant advantages over the conventional HPLC method, and the quantification can be directly realized and easily distinguished.

Strychnine, Nux vomica

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