Demographic and clinical features predictive of recovery in acute mania

Article Abstract:

Although lithium treatment is used widely to treat manic depressive psychosis, 20 to 30 percent of manic patients fail to respond to the drug. To investigate factors that might identify patients who could benefit from initial treatment with alternative drugs, 44 hospitalized patients with bipolar affective disorder (manic depression) were studied. On admission, they were given a psychiatric and a manic state rating scale. Upon discharge, they were divided into recovered and nonrecovered groups, determined by a multidisciplinary assessment including social work evaluation of families' perception of patients' recovery, nursing staff evaluations of patients' interpersonal and personal skills, and an evaluation of patients' occupational task skills. The recovered group was discharged to self-care with medication monitoring. The nonrecovered patients required further treatment and were all placed in halfway house facilities upon discharge. Analysis of the results revealed that 86.4 percent of the patients had recovered by the time of discharge. The average age of the recovered group (30.3 years) was found to be significantly older than that of the nonrecovered group (19.3). Overall scores on the psychiatric and manic rating scales, and degree of psychosis on admittance were not found to be related to outcome. The recovered group did have significantly lower average scores on one depressive scale item and a depressive subscale score as well as a significantly higher average scores on an item which rated looking happy and cheerful. Although there seems to be an association between less depressive symptomatology, older age at illness onset and good response to treatment with lithium, further investigation is called for. (Consumer Summary produced by Reliance Medical Information, Inc.)

Health aspects, Evaluation, Prognosis, Drug therapy, Bipolar disorder, Lithium, Lithium (Metal), Mania

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The equivalence of the Child Behavior Checklist/1 1/2-5 across parent race/ethnicity, income level and language

Article Abstract:

The equivalence of Child Behavior Checklist/1 1/2-5 (CBCL/1 1/2-5) was examined in 682 parents of 2- to 4 year-old children stratified by parent race/ethnicity, family income, and language version. Differential item analyses revealed that selected items functioned differently by racial/ethnic, language and income group.

Psychological aspects, Analysis, Behavior, Children, Child behavior, Preschool children, Child behaviour

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