Comment of "A Major Incident of Dioxin Contamination: Sediments of New Jersey Estuaries." (includes responses)

Article Abstract:

Research by Richard F. Bopp et al on dioxin contamination in New Jersey estuaries in the Newark Bay area is faulty, and the conclusion that a single chemical manufacturing facility is responsible for the pollution is not valid. For example, the study reported sediment core profiles taken at different depths but concluded, through statistical correlation, that chemical profiles could be matched to industrial activity during specific time periods. Other criticisms of the Bopp et al study are presented. Replies by Richard F. Bopp are also included.

Pollution, Estuaries

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A history of octachlorodibenzo-p-dioxin, 2,3,7,8-tetrachlorodibenzofuran, and 3,3',4,4'-tetrachlorobiphenyl contamination in Howe Sound, British Columbia

Article Abstract:

The source and distribution of 2,3,7,8-tetrachlorodibenzofuran (TCDF), octachlorodibenzo-p-dioxin (OCDD) and 3,3',4,4'-tetrachlorobiphenyl (TCB) in Howe Sound, British Columbia, was measured. The source of both OCDD and 3,3',4,4'-TCB seems to be the atmosphere, but 2,3,7,8-TCDF could come from pulp mill effluent discharges from as early as 1965, according to sediment samples. OCDD and 3,3',4,4'-TCB, which is also known as PCB 77, are widely distributed.

Environmental aspects, Polychlorinated biphenyls, British Columbia, Furans

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Relative susceptibility of animals and humans to the cancer hazard posed by 2,3,7,8-tetrachlorodibenzo-p-dioxin using internal measures of dose

Article Abstract:

The carcinogenic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) was analyzed in humans and rats. Dosage-controlled administration of the carcinogen indicated the high susceptibility of rat liver to the carcinogenic effects of TCDD. Furthermore, female rats exhibited liver tumors that were inhibited by the removal of ovaries. On the other hand, human workers who were exposed to the carcinogen for one year did not exhibit tissue carcinogenesis.

Analysis, Physiological aspects, Carcinogenesis, Carcinogens, Rats as laboratory animals, Laboratory rats

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