Molecular pathophysiology of Parkinson's disease

Article Abstract:

The molecular pathways involved in the pathogenesis of Parkinson's disease (PD) are discussed. The principle molecular pathways underlying the pathogenesis of sporadic and familial forms of PD are represented by mitochondrial dysfunction, oxidative and nitrosative stress, the accumulation of aberrant or misfolded proteins and impairment of ubiquitin-proteasome system.

Science & research, Research, Genetic aspects, Parkinson's disease, Parkinson disease, Pathology, Molecular, Molecular pathology, Oxidative stress, Ubiquitin-proteasome system

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Homeostatic control of neural activity: From phenomenology to molecular design

Article Abstract:

A restrictive definition of homeostasis is used to evaluate the phenomenological and molecular evidence for homeostatic signaling in nervous system. The analysis has proposed that homeostatic signaling will allow essential mechanisms of neural plasticity to persist but will constrain this plasticity to ensure that it drives constructive rather than destructive change.

Neuroplasticity, Homeostasis

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Molecular architecture of smell and taste in Drosophila

Article Abstract:

The article analyses the neuroanatomy, circuitry and molecular biology for characterization of chemical senses, smell and taste in 'Drosophila'. The results provide the insights of smell functions in all animals.

Research and Development in the Physical, Engineering, and Life Sciences, Molecular Biology, Physiological aspects, Drosophila, Neuroanatomy, Clinical report

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