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Role of beta-chemokines in suppressing HIV replication

Article Abstract:

Researchers who reported on CD8 T lymphocyte anti-HIV activity disagree with another group who concluded that three beta-chemokines are responsible for the activity. Beta-chemokines, as well as other cytokines, were not present in consistent or sufficient amounts to act as cell antiviral factors.

Author: Levy, Jay A., Garzino-Demo, Alfredo, Barker, Edward, Mackewicz, Carl E., Cocchi, Fiorenza, DeVico, Anthony L.
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1996
CD8 lymphocytes

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Herpes-like sequences in HIV-infected and uninfected Karposi's sarcoma patients

Article Abstract:

A study used the polymerase chain reaction procedure to analyze 13 Karposi's sarcoma biopsies, 12 normal biopsies, peripheral blood mononuclear cells and KS-derived cell lines. Results indicate a herpesvirus-like DNA sequence in all KS biopies, including one unaffected by HIV.

Author: Lennette, Evelyne T., Herndier, Brian G., Levy, Jay A., Ambtoziak, John A., Blackbourn, David J., Glogau, Richard G., Gullett, John H., McDonald, Alex R.
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1995
Herpesviruses, Kaposi's sarcoma

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Plasma viral load, CD4+ cell counts, and HIV-1 production by cells

Article Abstract:

Plasma viral load measurements are an important issue in evaluating the effectiveness of antiviral treatment of HIV-infected patients. Interpretations of research on the amount of virus produced by HIV-infected cells are discussed.

Author: Coffin, John M., Levy, Jay A., Ramachandran, Bineetha, Barker, Edward, Guthrie, Jessica, Elbeik, Tarek
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1996
Evaluation, HIV infection, HIV infections, Antiviral agents, Virus replication

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Subjects list: Research, HIV (Viruses), HIV
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